Morphological transformations of vesicles with confined filaments

• 主讲人：Xin Yi（Peking University）
• 举办方： Beijing-Moscow Mathematics Colloquium
• 时间： 2023-11-17 16:00 - 2023-11-17 17:00
• 地点： online

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Abstract: Packing of elastic filaments, encompassing cytoskeletal microtubules, actin filaments, and artificial nanotubes, is fundamental to understanding a wide range of cellular functions and their applications in cellular engineering. Through theoretical analysis, we examine the packing of open or closed filaments within vesicles, unveiling how the stiffness and size ratios between filaments and vesicles lead to transitions in vesicle configurations, inducing filament bending or coiling. Morphological phase diagrams are established to elucidate these shifts. These findings shed light on the understanding of cell morphology, cellular stability, and the construction of artificial cells in biomedical and engineering contexts.

 

Bio: Xin Yi received his B.E. and M.S. degrees from Peking University in 2005 and 2008, respectively, and his Ph.D. degree in Engineering Science at Brown University in 2014. He joined the faculty of Peking University in 2016 and was promoted to Associate Professor with tenure in 2023. His research is dedicated to advancing fundamental understanding of complex mechanical behaviors in materials, spanning both biological and engineering systems. His current focus involves investigating the interaction between cells and nanomaterials, as well as exploring the mechanics of nanostructured metals.